Figure 3. Seven of the 12 loci selected from our ovarian and endometrial cancer analysis show differential methylation in cancer vs. normal cell lines from ENCODE. The heat map shows β values that reflect the level of methylation associated with each probe (columns) in each cell line (rows). The color side bar on the left distinguishes cell lines that were derived from cancer (magenta), normal (green) or unspecified (black) tissues. Unsupervised hierarchical clustering based on pairwise correlations was used to order rows and columns. Median levels of methylation in cancer and normal cell lines are provided in Table 2.