Table 3.
Effects of khat extract on activity of renal antioxidant enzymes and levels of malondialdehyde in rats
| Groups | SOD (U/mg protein) | CAT (U/mg protein) | MDA (nmol/mg protein) |
|---|---|---|---|
|
CON |
259.50 ± 7.56 |
17.69 ± 0.73 |
2.60 ± 0.04 |
|
K100 |
249.49 ± 11.49 |
17.62 ± 0.56 |
2.86 ± 0.07 |
|
K200 |
240.66 ± 6.97 |
16.20 ± 0.40 |
3.68 ± 0.17a1 |
|
K400 |
221.17 ± 7.51a2 |
11.50 ± 0.87a3 |
5.30 ± 0.16a2 |
| GEN | 136.43 ± 4.94a3b3c3d3 | 6.54 ± 0.47 a3b3c3d3 | 6.27 ± 0.19a3b3c3d3 |
Values are mean ± SEM. n = 8; acompared to CON; bcompared to K100; ccompared to K200; dcompared to K400. 1p < 0.05; 2p < 0.01; 3p < 0.001. (CON: control, received Tween80; K100, khat 100 mg/kg; K200, khat 200 mg/kg; K400, khat 400 mg/kg; GEN, gentamicin 100 mg/kg; SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde).