Table 4.
Effects of khat and gentamicin co-administration on activity of renal antioxidant enzymes and levels of malondialdehyde in rats
| Groups | SOD (U/mg protein) | CAT (U/mg protein) | MDA (nmol/mg protein) |
|---|---|---|---|
| GEN |
136.43 ± 4.94 |
6.54 ± 0.47 |
6.273 ± 0.1974 |
| GK100 |
134.86 ± 3.23 |
5.72 ± 0.27 |
6.749 ± 0.1981 |
| GK200 |
126.08 ± 8.23 |
4.60 ± 0.18 |
6.935 ± 0.2460 |
| GK400 | 101.33 ± 3.48a3 | 3.31 ± 0.46a3 | 8.694 ± 0.2184a3 |
Values are mean ± SEM. n = 8; acompared to GEN; 3p < 0.001. (GEN: gentamicin 100 mg/kg; GK100: gentamicin 100 mg/kg + Khat 100 mg/kg; GK200: gentamicin 100 mg/kg + Khat 200 mg/kg; GK400: gentamicin 100 mg/kg + Khat 400 mg/kg; SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde).