Table 4.
Serum cardiovascular risk markers.
| Characteristics | Statin (n = 26) | No statin (n = 12) | P-value |
|---|---|---|---|
| CRP*, mg/L | 2.4 (0.96–4.03) | 4.1 (1.43–8.41) | 0.1782 |
| OPN, ng/mL | 17.5 (12.8–23.8) | 29.4 (23.2–34.6) | 0.0131 |
| RANKL, pg/mL | 1022 (247–1669) | 1839 (1551–2803) | 0.0050 |
| OPG, pg/mL | 167.8 (62.3–318.1) | 62.3 (62.3–432.0) | 0.0182 |
| RANKL/OPG ratio | 5.8 (1.5–17.1) | 27.2 (15.5–43.3) | 0.0004 |
| MPO, ng/mL | 265.2 (101.8–531.6) | 466.0 (313.7–841.9) | 0.1014 |
| Neutrophil elastase, ng/mL | 211.1 (109.1–318.6) | 325.3 (143.1–450.2) | 0.1489 |
| MMP†-8, ng/mL | 16.5 (5.8–23.7) | 12.7 (4.0–24.7) | 0.7579 |
| MMP-9, ng/mL | 231.5 (134.9–431.6) | 479.0 (352.8–812.5) | 0.0461 |
| Pro-MMP-9 activity, ng/mL | 6.8 (3.1–14.4) | 13.1 (11.9–18.2) | 0.0310 |
| MMP9/TIMP-1, ng/mL | 10.6 (6.4–18.4) | 14.4 (2.8–23.0) | 0.8839 |
| TIMP‡-1, ng/mL | 191.3 (120.0–216.7) | 211.0 (147.6–264.6) | 0.3389 |
| TIMP-2, ng/mL | 101.4 (65.4–124.5) | 97.0 (73.0–112.2) | 0.8078 |
| TIMP-3, ng/mL | 8.1 (4.7–14.9) | 12.5 (6.2–13.8) | 0.5824 |
| TIMP-4, ng/mL | 5.4 (3.6–6.6) | 4.2 (4.0–6.1) | 0.7579 |
Data are expressed as median (interquartile range (IQR)).
*CRP: C-reactive protein.
†MMP: matrix metalloproteinase.
‡TIMP: tissue inhibitor of metalloproteinase.