Table 6.
Spearman rank correlation between serum RANKL/OPG ratio and systemic and intraplaque parameters (upstream or downstream regions) of vulnerability.
| Spearman's correlation coefficient (r) | P-value | |
|---|---|---|
| Serum RANKL/OPG ratio | ||
| Systemic | ||
| CRP, mg/L | 0.3549 | 0.0311 |
| MPO, ng/mL | 0.6036 | 0.0001 |
| Neutrophil elastase, ng/mL | 0.5223 | 0.0009 |
| MMP-8, ng/mL | 0.0436 | 0.7977 |
| MMP-9, ng/mL | 0.3106 | 0.0614 |
| Pro-MMP-9 activity, ng/mL | 0.3248 | 0.0498 |
| Intraplaque upstream | ||
| versus lipids | −0.3456 | 0.0489 |
| versus total collagen | 0.0077 | 0.9661 |
| versus collagen I | 0.0879 | 0.6267 |
| versus collagen III | 0.0906 | 0.6162 |
| versus SMCs | −0.0832 | 0.6452 |
| versus macrophages | −0.0552 | 0.7605 |
| versus neutrophils | 0.1180 | 0.5132 |
| versus MMP-9 | −0.2647 | 0.1366 |
| Intraplaque downstream | ||
| versus lipids | −0.0946 | 0.5947 |
| versus total collagen | −0.1383 | 0.4355 |
| versus collagen I | −0.1636 | 0.3551 |
| versus collagen III | −0.0805 | 0.6508 |
| versus SMCs | −0.0118 | 0.9473 |
| versus macrophages | 0.2461 | 0.1605 |
| versus neutrophils | 0.3756 | 0.0285 |
| versus MMP-9 | 0.3510 | 0.0418 |