Table 2. Brain regions with significant differences in ReHo between control and POAG group (P(corrected)<0.05, P(uncorrected)<0.005 and cluster voxels>26).
Brain areas | Hemisphere | BA | MNI coordinates (cluster maxima, mm) | Peak T values | Cluster size (voxels) | ||
X | Y | Z | |||||
POAG<CON | |||||||
Dorsal Cingulate Cortex | Right | 33 | 6 | 18 | 24 | 3.97 | 47 |
Medial Superior Frontal Gyrus | Bilateral | 0 | 27 | 63 | 3.71 | 90 | |
Medial Frontal Gyrus | Bilateral | 9 | 12 | 36 | 33 | 3.45 | 64 |
Cerebellum Anterior Lobe | Right | 24 | −42 | −36 | 3.09 | 31 | |
POAG<CON | |||||||
Calcarine | Left | 17 | −3 | −90 | 0 | 4.13 | 132 |
Calcarine/Lingual Gyrus | Right | 18 | 15 | −75 | 0 | 4.13 | 97 |
Precentral/Postcentral Gyrus | Left | 4 | −60 | −18 | 36 | 3.78 | 57 |
Precentral/Postcentral Gyrus | Right | 3 | 57 | −18 | 33 | 3.75 | 68 |
Occipital/Cerebellum Posterior Lobe | Left | −27 | −63 | −9 | 3.58 | 87 | |
Precuneus | Left | −12 | −45 | 69 | 3.55 | 55 | |
Precuneus | Right | 15 | −72 | 39 | 3.51 | 39 | |
Inferior Parietal Lobule | Left | −45 | −39 | 48 | 3.14 | 27 |
BA Brodmann area; MNI: Montreal Neurological Institute;
ReHo: regional homogeneity; POAG: primary open-angle glaucoma;