Fig. 1.
Synthesis scheme and spectral characterization of metapristone. a the synthetic route for metapristone; b UV–visible spectra of metapristone and the solvent effects: b1, metapristone in alcohol (b1) and methanol (b2) solvents; the UV–vis absorption maxima of metapristone decreased when the carbon chain of alcohol as well as the percentage of water in methanol increased. c representative HPLC analysis (c1) and infrared spectra (c2); d the 1H-NMR (d1) and mass (d2) spectra of metapristone