Table 4.
AMHRII -482 A>G homozygote mutation, all of which were accompanied with ISV 5-6 C>T homozygote mutation, showed a statistically lower oocyte retrieval rate (28.5 %) and pregnancy rate (0 %) in comparison with the wild type; however, other homozygote mutations of AMH and AMHRII showed no statistical difference in their oocyte retrieval rate, fertilization rate, and pregnancy rate
| Polymorphism (N = 80) | Aspirated follicle | Retrieved oocyte | Oocyte retrieved rate | Fertilization rate (%) | Pregnancy rate (%) | |
|---|---|---|---|---|---|---|
| AMH 146 T>G | Homo (n = 12) | 96 | 48 | 50.0 | 68.8 | 27.2 |
| Wild (n = 27) | 266 | 155 | 58.2 | 72.9 | 29.3 | |
| AMHR -482 A>G | Homo (n = 3) | 21 | 6 | 28.5a | 50.0 | 0b |
| Wild (n = 45) | 503 | 276 | 54.8 | 71.0 | 28.1 | |
| AMHR ISV5-6 C>T | Homo (n = 5) | 49 | 22 | 44.8 | 72.7 | 0b |
| Wild (n = 36) | 436 | 245 | 56.8 | 69.8 | 19.4 | |
| AMHR ISV10+77 A>G | Homo (n = 3) | 17 | 7 | 41.1 | 71.4 | 33.3 |
| Wild (n = 21) | 249 | 126 | 50.6 | 73.0 | 14.2 | |
X 2 test
a,b p < 0.05