Table 3.
Reported miRNAs deregulated by heat stress
| Citation | Organism | Tissue/cell type | Heat stress | Deregulated miRNAsa |
|---|---|---|---|---|
| Yu et al. 2011 | Sprague–Dawley rats | Small intestine tissue | 40 °C for 2 h over 10 consecutive days | UP: miR-34b, -137, -154, -672, -219-5p, -375, -7a, -34a, -30a*, -500, -185, -203, -200a, -140*, let-7d, -125a-5p, -27b, -210 |
| DOWN: miR-322, -142-5p, -434, -204, -142-3p, -193, -31, -150, -148b-3p, -223, -23a | ||||
| Yin et al. 2008 | ICR mice | Heart tissue | 42 °C for 15 min with 2 h recovery at RT | UP: miR-1, -21, -24 |
| DOWN: not reported/evaluated | ||||
| Oshlag et al. 2013 | Human | Hela and JAR cell lines | 39.5 °C for 1.5 to 8 h | UP: miR-125b, -154, -382 |
| DOWN: not reported/evaluated | ||||
| Wilmink et al. 2010 | Human | HDF cells in culture | 44 °C for 40 min with 4 h recovery at RT | UP: miR-125b, -452, -133b, -192, -382, -378, -101, -424, -22 |
| DOWN: miR-138, -7, -376a, -31, -222, -33a, -29b, -606, let-7c, let-7d, - 218, -196a, -204, -196b, -154, -1298, -18a, -487b |
ICR imprinting control region, RT room temperature, UP upregulated miRNAs, DOWN downregulated miRNAs
amiRNA sequences correspond to cognate species