. 2013 Jul 28;19(2):205–215. doi: 10.1007/s12192-013-0446-7

Table 1.

Genotype and allele distributions for the HSPA1A (+190G/C), HSPA1B (+1267A/G), and HSPA1L (+2437T/C) polymorphisms in paranoid schizophrenia patients (n = 203) and control subjects (n = 243)

Polymorphisms	N (%)
Polymorphisms	Genotype					Allele
HSPA1A (rs1043618)	GG	GC	CC	χ ²	p	G	C	χ ²	p
Patients	94 (46.3)	76 (37.4)	33 (16.3)	13.45	<0.01	264 (65.0)	142 (35.0)	10.35	<0.01
Control	135 (55.5)	94 (38.7)	14 (5.8)	13.45	<0.01	364 (75.0)	122 (25.0)	10.35	<0.01
Male patients	52 (46.0)	42 (37.2)	19 (16.8)	6.17	<0.05	146 (64.6)	80 (35.4)	5.42	<0.05
Male controls	83 (55.4)	56 (37.3)	11 (7.3)	6.17	<0.05	222 (74.0)	78 (26.0)	5.42	<0.05
Female patients	42 (46.7)	34 (37.8)	14 (15.5)	8.36	<0.05	118 (65.6)	62 (34.4)	5.18	<0.05
Female controls	52 (55.9)	38 (40.9)	3 (3.2)	8.36	<0.05	142 (76.3)	44 (23.7)	5.18	<0.05
HSPA1B (rs1061581)	AA	AG	GG	χ ²	p	A	G	χ ²	p
Patients	84 (41.4)	89 (43.8)	30 (14.8.)	0.01	0.9999	257 (63.3)	149 (36.7)	0.01	0.9999
Control	100 (41.2)	107 (44.0)	36 (14.8)	0.01	0.9999	307 (63.2)	179 (36.8)	0.01	0.9999
Male patients	47 (41.6)	48 (42.5)	18 (15.9)	0.33	0.8479	142 (62.8)	84 (37.2)	0.07	0.7913
Male controls	58 (38.7)	69 (46.0)	23 (15.3)	0.33	0.8479	185 (61.7)	115 (38.3)	0.07	0.7913
Female patients	37 (41.1)	41 (45.6)	12 (13.3)	0.42	0.8106	115 (63.9)	65 (36.1)	0.12	0.7290
Female controls	42 (45.1)	38 (40.9)	13 (14.0)	0.42	0.8106	122 (65.6)	64 (34.4)	0.12	0.7290
HSPA1L (rs2227956)	TT	TC	CC	χ ²	p	T	C	χ ²	p
Patients	139 (68.5)	59 (29.0)	5 (2.5)	0.53	0.7672	337 (83.0)	69 (17.0)	0.47	0.5214
Control	174 (71.6)	64 (26.3)	5 (2.1)	0.53	0.7672	412 (84.8)	74 (15.2)	0.47	0.5214
Male patients	76 (67.2)	35 (31.0)	2 (1.8)	–	0.5327	187 (82.7)	39 (17.3)	0.84	0.3594
Male controls	108 (72.0)	41 (27.3)	1 (0.7)	–	0.5327	257 (85.7)	43 (14.3)	0.84	0.3594
Female patients	63 (70.0)	24 (26.7)	3 (3.3)	–	0.9250	150 (83.3)	30 (16.7)	0	1
Female controls	66 (71.0)	23 (24.7)	4 (4.3)	–	0.9250	155 (83.3)	31 (16.7)	0	1

All data in italics are statistically significant