Table 3.
Organism | p (degree) | p (Betweenness centrality) | p (Closeness centrality) | p (Pairwise disconnectivity index) |
---|---|---|---|---|
Acinetobacter baylyi | < 10−6 | < 10−6 | 0.22 | 0.14 |
Arabidopsis thaliana | 8.52 × 10−3 | 0.05 | 0.18 | 0.15 |
Bacillus subtilis | < 10−6 | < 10−6 | 0.89 | 0.40 |
Caenorhabditis elegans | 8.40 × 10−5 | 0.25 | 0.10 | 0.01 |
Escherichia coli | < 10−6 | < 10−6 | 0.92 | 0.98 |
Francisella novicida | < 10−6 | < 10−6 | 0.50 | 0.49 |
Haemophilus influenzae | < 10−6 | 0.26 | 0.22 | 0.36 |
Helicobacter pylori | < 10−6 | 6.55 × 10−4 | 0.86 | 0.03 |
Mycobacterium tuberculosis | < 10−6 | < 10−6 | 0.20 | 0.07 |
Mycoplasma genitalium | < 10−6 | 0.05 | 0.76 | 0.18 |
Mycoplasma pulmonis | < 10−6 | < 10−6 | 0.87 | 0.00 |
Pseudomonas aeruginosa | < 10−6 | < 10−6 | 0.14 | 0.05 |
Saccharomyces cerevisiae | < 10−6 | < 10−6 | 0.28 | 0.09 |
Salmonella enterica serovar typhi | < 10−6 | < 10−6 | 0.92 | 0.06 |
Salmonella typhimurium | < 10−6 | 0.0163 | 0.85 | 0.15 |
Staphylococcus aureus NCTC | < 10−6 | < 10−6 | 0.24 | 0.18 |
Staphylococcus aureus subsp. aureus N315 | < 10−6 | < 10−6 | 0.96 | 0.05 |
Streptococcus pneumoniae | 2 × 10−6 | 7.14 × 10−4 | 0.57 | 0.11 |
Streptococcus sanguinis | < 10−6 | < 10−6 | 0.61 | < 10−6 |
Vibrio cholerae | < 10−6 | < 10−6 | 0.57 | 0.89 |
Poor p values (p > 0.01) have been shown in bold. The table clearly shows that metrics such as closeness centrality and pairwise disconnectivity index cannot be used to selectively delineate essential nodes