Table 4.
Fraction of essential proteins in the top 10 % of nodes (by degree, by betweenness centrality)
| Organism | Nodes (proteins) |N0| | Essential nodes in N0 | (%) |
|
Essential nodes in 
|
(%) |
|
Essential nodes in 
|
(%) |
|---|---|---|---|---|---|---|---|---|---|
| Acinetobacter baylyi | 2,546 | 468 | (18.4) | 258 | 138 | (53.5) | 257 | 101 | (39.3) |
| Arabidopsis thaliana | 7,090 | 195 | (2.8) | 717 | 29 | (4.0) | 710 | 24 | (3.4) |
| Bacillus subtilis | 3,347 | 219 | (6.5) | 338 | 71 | (21.0) | 335 | 53 | (15.8) |
| Caenorhabditis elegans | 5,184 | 192 | (3.7) | 519 | 34 | (6.6) | 519 | 27 | (5.2) |
| Escherichia coli | 3,789 | 672 | (17.7) | 407 | 150 | (36.9) | 379 | 118 | (31.1) |
| Francisella novicida | 1,415 | 362 | (25.6) | 147 | 102 | (69.4) | 142 | 63 | (44.4) |
| Haemophilus influenzae | 1,497 | 592 | (39.5) | 160 | 89 | (55.6) | 150 | 62 | (41.3) |
| Helicobacter pylori | 1,352 | 298 | (22.0) | 140 | 48 | (34.3) | 136 | 40 | (29.4) |
| Mycobacterium tuberculosis | 3,295 | 587 | (17.8) | 330 | 109 | (33.0) | 330 | 99 | (30.0) |
| Mycoplasma genitalium | 446 | 363 | (81.4) | 45 | 45 | (100.0) | 46 | 40 | (87.0) |
| Mycoplasma pulmonis | 616 | 288 | (46.8) | 63 | 61 | (96.8) | 62 | 45 | (72.6) |
| Pseudomonas aeruginosa | 4,556 | 296 | (6.5) | 468 | 77 | (16.5) | 456 | 61 | (13.4) |
| Saccharomyces cerevisiae | 5,477 | 1,109 | (20.2) | 548 | 240 | (43.8) | 548 | 159 | (29.0) |
| Salmonella enterica serovar typhi | 3,491 | 344 | (9.9) | 355 | 103 | (29.0) | 350 | 66 | (18.9) |
| Salmonella typhimurium | 3,712 | 204 | (5.5) | 395 | 45 | (11.4) | 372 | 37 | (9.9) |
| Staphylococcus aureus NCTC | 2,127 | 328 | (15.4) | 221 | 128 | (57.9) | 213 | 72 | (33.8) |
| Staphylococcus aureus subsp. aureus N315 | 1,966 | 296 | (15.1) | 200 | 115 | (57.5) | 197 | 68 | (34.5) |
| Streptococcus pneumoniae | 1,718 | 109 | (6.3) | 180 | 25 | (13.9) | 172 | 22 | (12.8) |
| Streptococcus sanguinis | 1,801 | 215 | (11.9) | 181 | 80 | (44.2) | 181 | 58 | (32.0) |
| Vibrio cholerae | 2,958 | 537 | (18.2) | 314 | 130 | (41.4) | 296 | 83 | (28.0) |
The table lists all organisms considered in this study, along with the numbers and fraction of essential nodes in the entire network, as well as for sets of nodes with the highest degree or betweenness centralities. The table clearly illustrates the enrichment of essential nodes in the N90 sets: in all cases, there is an increase in the fraction of essential proteins in the N 90 sets, more so in some organisms compared to others