a Path scores of the different weighting schemes for the 86 RPs. Sc3 and sc5 show consistent higher values, while sc6 consistently shows lower values. b Heat map showing the scores obtained by each path by the different weighting schemes (sc1, sc2, sc3, sc4, sc5, sc6); top panel represents the 86 RPs and the bottom panel shows 1,066 TPs. Higher density of blue is seen for sc1 and sc2 in the top panel. It should also be noted that sc6 shows lower scores for all the paths. (Color figure online)