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. 2014 Feb 24;9(2):e89584. doi: 10.1371/journal.pone.0089584

Figure 1. Physical characteristics, neuromuscular strength, motor coordination, nociception, and gait in CD47 KO and wild-type mice.

Figure 1

No significant differences between genotypes were detected in body weight (A), body temperature (B), grip strength (C), or latency to fall in the wire hang test (D). (E) Likewise, no significant differences between the genotypes were observed in latency to fall from the rotarod (F) or latency to the first paw response in the hot plate test. CD47 KO mice, n = 20; wild-type mice, n = 20. (G–H) CD47 KO mice were also subjected to gait analysis. (G) The mutants showed significant decreases in stance width for front and hind paws compared to wild-type mice. (H) Paw angles for hind paws, but not for front paws, were significantly narrower in the mutants than in wild-type mice. CD47 KO mice, n = 19; wild-type mice, n = 20.