Table 1. Clinical characteristic of untreated patients with early polymyositis and controls.
Clinical characteristic | Patients (n = 60) | Controls (n = 60) |
Age (years) | 42.9±12.5 | 42.9±11.7 |
F/M | 44/16 | 44/16 |
Smoking (n, %) | 6/60 (10) | 7/60 (10) |
Drinking (n, %) | 5/60 (8.3) | 6/60 (10) |
Body mass index (kg/m2) | 22.7±2.8 | 22.1±2.6 |
systolic pressure (mmHg) | 117.1±11.3 | 118.2±10.5 |
diastolic pressure (mmHg) | 75.7±6.2 | 74.9±7.5 |
Respiratory tiredness (n, %) | 7/60 (12) | 0/60 (0) |
Myalgia (n, %) | 45/60 (75) | 0/60 (0) |
Muscle weakness (n, %) | 45/60 (75) | 0/60 (0) |
Myoedema (n, %) | 13/60 (22) | 0/60 (0) |
Arthralgia (n, %) | 22/60 (37) | 0/60 (0) |
Raynaud's phenomenon (n, %) | 9/60 (15) | 0/60 (0) |
Dysphagia (n, %) | 6/60 (10) | 0/60 (0) |
Pulmonary fibrosis/infection (n,%) | 29/60 (48) | NA |
Positive ANA (n, %) | 44/60 (73) | NA |
Positive anti-Jo-1 antibody (n, %) | 7/60 (12) | NA |
Elevated triglyceride (n, %) normal range: 0.29–1.83 mmol/L | 28/60 (47) | 12/60 (20)* |
Elevated total cholesterol (n, %) normal range: 2.8–5.7 mmol/L | 3/60 (5) | 5/60 (8) |
Elevated LDL-cholesterol (n, %) normal range: <4.0 mmol/L | 0/60 (0) | 4/60 (7) |
Reduced HDL-cholesterol (n, %) normal range: >0.9 mmol/L | 30/60 (50) | 0/60 (0)* |
Positive CRP (n, %) normal range: <5.0 mg/L | 36/60 (60) | 4/60 (7)* |
CRP levels | 11.6±13.9 | 3.3±1.2* |
F, female; M, male; CRP, C-reactive protein; HDL-C, high-density lipoprotein -cholesterol; LDL-C, low-density lipoprotein- cholesterol; NA, not available.
* P<0.05.