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. 2014 Feb 24;9(2):e89811. doi: 10.1371/journal.pone.0089811

Figure 2. TCDD induced the expression of senescence marker proteins in a dose-dependent manner.

Figure 2

PC12 cells were exposed to different doses of TCDD for 72(A) and semi-quantitative PCR (B) analyses to determine the protein and mRNA levels of p16 (* p<0.05, significantly different from the DMSO-treated group). (C) The expression of p21 and p-Rb was also evaluated using a western blot analysis (* p<0.05, significantly different from the DMSO-treated group).