Table 1. ED50 values of antibiotics in the honeybee S. aureus infection model.
Antibiotics | A. mellifera L. | A. mellifera L. | B. mori a | B. mori a |
i.c. | p.o. | i.h. | p.o. | |
Tetracycline | 0.2b | 2 | 0.4 | 8 |
Vancomycin | 0.02 | >330 | 0.3 | >400 |
Kanamycin | 0.4 | >330 | 3 | >500 |
ED50 values of tetracycline, vancomycin, and kanamycin against S. aureus infection in in-hive worker bees (n = 5) were determined 24 h after infection. Antibiotics were injected into the cavities (i.c.) or orally administered (p.o.), and live bacterial suspension of S. aureus was injected immediately after antibiotic treatment.
ED50 values of B. mori were previously reported [16].
µg/insect.