Table 2.

Brain regions showing increased/decreased ALFF in PBD versus HC subjects

Brain regions of ALFF	Side	BA	Talairach coordinates (MNI)			t-statistic	K
PBD vs HC			X	Y	Z
PBD > HC
Caudate	Left		−15.00	6.00	15.00	4.18	42
Caudate	Right		12.00	6.00	15.00	4.05	55
Pallidum	Left		−15.00	6.00	−3.00	3.52	10
PBD < HC
Precuneus	Left	7	−18.00	−63.00	57.00	−5.78	10
Superior parietal lobule	Left	7	−24.00	−69.00	45.00	−4.02	37
Inferior occipital gyrus	Left	18	−30.00	−87.00	−15.00	−3.55	18
Inferior occipital gyrus	Right	18	42.00	−84.00	−15.00	−3.35	13

Abbreviations: ALFF, amplitude of low-frequency fluctuation; BA, Brodmann area; HC, healthy controls; PBD, pediatric bipolar disorder; K, cluster size in 3 × 3 × 3 mm³ voxels; MNI, Montreal Neurological Institute.