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. Author manuscript; available in PMC: 2014 Feb 25.
Published in final edited form as: Stroke. 2013 Jun 6;44(8):2284–2291. doi: 10.1161/STROKEAHA.113.001320

Figure 3.

Figure 3

Cerebral perfusion and cerebrovascular regulation are not compromised in lipoprotein receptor–related protein-6 (LRP6)+/− mice. Core (A) and penumbral (B) blood flow during and after middle cerebral artery occlusion (MCAo; n=5/group). C, Intraarterial blood pressure recordings in mice undergoing MCAo (n=5/group). D, Cerebral blood flow (CBF) responses in LRP6+/+ or LRP6+/− mice undergoing whisker stimulation or topical application of acetylcholine, bradykinin, or adenosine. Significance was tested by ANOVA followed by the Newman–Keuls test (A–C) or Student t test (D). MAP indicates mean arterial pressure.