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. 2014 Mar;143(3):325–343. doi: 10.1085/jgp.201311108

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© 2014 Yamashita and Prakriya

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Figure 7. — Noise analysis of 2-APB activation of Orai3 currents. (A) The mean current (I) and variance (δ²) during Orai3 channel activation by 2-APB (50 µM). Na⁺ currents in DVF solution activated by 2-APB were measured during 200-ms sweeps at a constant potential of −100 mV. (B) Variance analysis of the 2-APB–activated WT Orai3 Na⁺ current from the experiment shown in A. The data are well fit by a line with slope of 77 fA.