Skip to main content
. 2014 Mar;143(3):325–343. doi: 10.1085/jgp.201311108

Table 1.

Parameters of Ca2+ blockade of Na+ Orai3 currents

Channel type Ki n kon koff Unitary current
µM M−1s−1 s−1 fA
Orai3 (STIM1-gated) 25 1.2 4 × 106 33 71
Orai3 (2-APB–gated) 26 1.2 3 × 107 246 283
E81D Orai3 (STIM1-gated) 111 1.0 4 × 105 130
E81D Orai3 (2-APB–gated) 154 1.0
E165A Orai3 (2-APB–gated) 32 1.2

–, not determined.