Molecular intestinal microflora analysis in long-term C. jejuni B2
infected infant mice. Main gut bacterial groups were quantified by molecular analysis
of fecal samples before (N, naïve, open circles; n = 10) and after
C. jejuni B2 infection of infant mice (d103 p.i., solid circles;
n = 10). Quantitative real-time-PCR (polymerase chain reaction)
analyses amplified bacterial 16S rRNA variable regions and 16S rRNA gene numbers per
nanogram DNA. From feces the following bacterial groups were determined:
Enterobacteriaceae (EB), enterococci (EC), lactic acid bacteria
(LB), Bifidobacteria (BB), Bacteroides/Prevotella
spp. (BP), Clostridium leptum group (CLEP), Clostridium
coccoides group (CLOCC), mouse intestinal bacteroidetes (MIB), and total
eubacterial load (TL). Numbers of animals harboring the respective bacterial rRNA are
given in parentheses. Medians and significance levels (P-values)
determined by Mann–Whitney-U test are indicated. Data shown were pooled from three
independent experiments.