Table 1.
Characteristics of the dermatomyositis cases, controls and SNP data included in the study
| Population | Cases |
Controls |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Adult dermatomyositis | Juvenile dermatomyositis |
No. of successfully genotyped SNPs |
Covariate | Genomic inflation factor (λ) | |||||
| Sample size | Female (%) |
Sample size | Female (%) |
Sample size |
Female (%) |
||||
| Czech/Hungarian | 178 | 70.8% | 23 | 78.3% | 256 | 57.4% | 242530 | Population structure | 1.01 |
| Spanish | 43 | 81.4% | 4 | 50.0% | 259 | 65.6% | 242871 | Population structure | 1.009 |
| Swedish/Dutch | 48 | 68.8% | 4 | 75.0% | 642 | 72.4% | 242644 | Population structure | 1.021 |
| UK | 149 | 65.8% | 159 | 70.4% | 2415 | 47.8% | 236039 | None | 1 |
| USA | 287 | 76.0% | 283 | 69.6% | 1152 | 70.8% | 237155 | Population structure | 1.073 |
| Meta-analysis | 705 | 72.4% | 473 | 70.2% | 4724 | 58.2% | 241502 | None | 1.043 |