Table I.
Induction Method | Strain | Genotype | Incidence | Mean day of onseta | Mean maximum scorea | Recovery |
---|---|---|---|---|---|---|
Active | C3H/Fej | WT | 88% (7/8) | 18 ± 5 | 5.0 ± 0.3 | 0/7 |
Active | C3H/Fej | μMT | 33% (5/15)b | 21 ± 4 | 4.9 ± 0.5 | 0/5 |
Active | C3H.SW | WT | 100% (6/6) | 14 ± 1 | 3.1 ± 0.1 | 3/6 |
Active | C3H.SW | μMT | 50% (5/10)c | 15 ± 4 | 3.6 ± 0.2 | 3/5 |
Passive | C3H/Fej | WT | 96% (29/30) | 6.7 ± 0.9 | 4.6 ± 1.3 | 0/29 |
Passive | C3H/Fej | μMT | 21% (6/28)d | 6.6 ± 0.5 | 4.3 ± 1.9 | 0/6 |
Data shown (mean ± SEM) are from mice with EAE. p values indicating significant differences between WT vs μMT mice are as follows:
p=0.01,
p=0.03,
p<0.0001, Chi-squared test.