Table I.

Influence of μMT genotype on susceptibility of C3HeB/Fej and C3H.SW mice to EAE

Induction Method	Strain	Genotype	Incidence	Mean day of onseta	Mean maximum scorea	Recovery
Active	C3H/Fej	WT	88% (7/8)	18 ± 5	5.0 ± 0.3	0/7
Active	C3H/Fej	μMT	33% (5/15)b	21 ± 4	4.9 ± 0.5	0/5
Active	C3H.SW	WT	100% (6/6)	14 ± 1	3.1 ± 0.1	3/6
Active	C3H.SW	μMT	50% (5/10)c	15 ± 4	3.6 ± 0.2	3/5
Passive	C3H/Fej	WT	96% (29/30)	6.7 ± 0.9	4.6 ± 1.3	0/29
Passive	C3H/Fej	μMT	21% (6/28)d	6.6 ± 0.5	4.3 ± 1.9	0/6

^aData shown (mean ± SEM) are from mice with EAE. p values indicating significant differences between WT vs μMT mice are as follows:

^bp=0.01,

^cp=0.03,

^dp<0.0001, Chi-squared test.