. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: J Immunol. 2013 Dec 23;192(3):929–939. doi: 10.4049/jimmunol.1302171

Table II.

mRNA fold induction of immune mediators in the brains of mice with preclinical EAE relative to healthy tissue

Gene	Wildtype^a	μMT^a	p value^b
CXCL1	17.5 ± 3.7	1.9 ± 0.4	0.001
CXCL2	3.8 ± 0.9	0.9 ± 0.2	0.004
CXCL9	17.2 ± 2.9	5.5 ± 1.8	0.01
CXCL10	126.4 ± 27.2	12.3 ± 3.3	0.001
CCL2	47.4 ± 12.8	5.9 ± 2.1	0.008
CCL4	2.8 ± 0.4	0.8 ± 0.1	0.001
CCL7	19.2 ± 4.8	1.9 ± 0.4	0.002
CCL20	3.8 ± 0.9	1.1 ± 0.3	0.01
IL-1β	2.1 ± 0.4	0.3 ± 0.06	0.002
IL-6	13.1 ± 3.3	1.7 ± 0.4	0.004
E-selectin	22.4 ± 7.8	5.3 ± 2.4	0.01
P-selectin	49.4 ± 14	11.6 ± 4.1	0.01
ICAM	3.9 ± 0.5	0.9 ± 0.1	0.001

mRNA fold induction (mean ± SEM) determined from brain tissue of at least 6 mice harvested 5 days post-transfer.

Significant differences between WT and μMT recipients are indicated with the corresponding p values, Mann-Whitney non-parametric t test.