Table II.
Gene | Wildtypea | μMTa | p valueb |
---|---|---|---|
CXCL1 | 17.5 ± 3.7 | 1.9 ± 0.4 | 0.001 |
CXCL2 | 3.8 ± 0.9 | 0.9 ± 0.2 | 0.004 |
CXCL9 | 17.2 ± 2.9 | 5.5 ± 1.8 | 0.01 |
CXCL10 | 126.4 ± 27.2 | 12.3 ± 3.3 | 0.001 |
CCL2 | 47.4 ± 12.8 | 5.9 ± 2.1 | 0.008 |
CCL4 | 2.8 ± 0.4 | 0.8 ± 0.1 | 0.001 |
CCL7 | 19.2 ± 4.8 | 1.9 ± 0.4 | 0.002 |
CCL20 | 3.8 ± 0.9 | 1.1 ± 0.3 | 0.01 |
IL-1β | 2.1 ± 0.4 | 0.3 ± 0.06 | 0.002 |
IL-6 | 13.1 ± 3.3 | 1.7 ± 0.4 | 0.004 |
E-selectin | 22.4 ± 7.8 | 5.3 ± 2.4 | 0.01 |
P-selectin | 49.4 ± 14 | 11.6 ± 4.1 | 0.01 |
ICAM | 3.9 ± 0.5 | 0.9 ± 0.1 | 0.001 |
mRNA fold induction (mean ± SEM) determined from brain tissue of at least 6 mice harvested 5 days post-transfer.
Significant differences between WT and μMT recipients are indicated with the corresponding p values, Mann-Whitney non-parametric t test.