Table 2. Effect of Nocturnin knockdown on the development of early mouse embryos.
Injected vectors | No. (%) of embryos | No. (%) of embryos developed to | ||||||||
Injected | Survived | Expressed | 1-cell | 2-cell | 4-cell | 6 to 8-cell | Morulae | Blastocysts | Degenerated | |
Control | 341 | 252 (74) | 204 (81) | 204 (100) | 156 (76) | 130 (64) | 114 (56) | 99 (49) | 83 (41) | 77 (38) |
Antisense Nocturnin | 545 | 324 (59) | 88 (27) | 88 (100) | 61 (69) | 52 (59) | 43 (49) | 33 (38) | 28 (32) | 34 (39) |