Table 1.

Effect of cinacalcet treatment on biochemical indices of calcium homeostasis in a patient with X-linked dominant hypophosphatemia.

Plasma (reference interval)	Before cinacalcet treatment	During cinacalcet treatment	P value
PTH, pmol/L (1.6–6.9)	9.3 ± 3.3	5.4 ± 3.2	0.03
Calcium-ionized, mmol/L (1.18–1.32)	1.25 ± 0.03	1.15 ± 0.04	<0.01
Phosphate, mmol/L (0.76–1.41)	0.84 ± 0.10	0.80 ± 0.08	0.46
Alkaline phosphatase U/L (35–105)	94 ± 7	118 ± 8	<0.001
Calcidiol, nmol/L (50–160)	72 ± 20	72 ± 8	0.96
Creatinine, μmol/L (45–90)	58 ± 2	61 ± 4	0.17

Mean plasma levels (±standard deviation) in the three years prior to the start of treatment and during three years of treatment with cinacalcet. P values denote difference in mean values.