. 2014 Mar;133(3):375–385. doi: 10.1542/peds.2013-2903

APPENDIX 4.

Antibiotic-Dispensing Rate Per Person-Year for Second-Generation Macrolides and the Cephalosporins, 2000–2001 Compared With 2009–2010

Age	Plan	Second-Generation Macrolide Rate/Person-Year		First-Generation Cephalosporin Rate/Person-Year		Second-Generation Cephalosporin Rate/Person-Year		Third-Generation Cephalosporin Rate/Person-Year
		2000–2001	2009–2010	2000–2001	2009–2010	2000–2001	2009–2010	2000–2001	2009–2010
3 to <24 mo
	A	0.27	0.23	0.05	0.04	0.11	0.06	0.08	0.13
	B	0.09	0.05	0.05	0.04	0.11	NA^a	0.01	0.15
	C	0.34	0.30	0.05	0.05	0.25	0.07	0.04	0.22
2 to <4 years
	A	0.24	0.23	0.06	0.06	0.06	0.03	0.04	0.07
	B	0.06	0.06	0.05	0.05	0.04	NA^a	0.01	0.08
	C	0.22	0.23	0.06	0.05	0.12	0.04	0.01	0.11
4 to <6 y
	A	0.20	0.23	0.06	0.07	0.05	0.03	0.03	0.05
	B	0.05	0.05	0.05	0.05	0.02	NA^a	NA^a	0.04
	C	0.16	0.21	0.06	0.05	0.08	0.03	0.01	0.07
6 to <12 y
	A	0.13	0.16	0.06	0.08	0.03	0.02	0.01	0.02
	B	0.03	0.05	0.04	0.04	0.01	NA^a	NA^a	0.01
	C	0.11	0.16	0.06	0.05	0.04	0.02	NA^a	0.03
12 to <18 y
	A	0.11	0.14	0.07	0.08	0.02	0.01	NA^a	0.01
	B	0.03	0.06	0.05	0.04	0.01	0.01	NA^a	NA^a
	C	0.08	0.13	0.06	0.06	0.02	0.02	NA^a	0.01

All changes from 2000–2001 to 2009–2010 were statistically significant (p <0.001). NA, not applicable.

^{^a}

Antibiotic rate <0.01 dispensing per person-year.