Table I.
Biochemical and anthropometric parameters in 260 subjects with varying glucose status, grouped according to fasting and post-load glucose levels.
| Parameters | NG (n = 71) | I-IFG (n = 93) | I-IGT (n = 49) | Mixed IFG/IGT (n = 47) |
|---|---|---|---|---|
| Age (years)a | 65.13±6.17 | 65.29±6.13 | 66.9±5.64 | 64.63±5.89 |
| Sex (% male) | 21.1 | 28.6 | 31.3 | 39.1c |
| Fasting glucose (mmol/L)b | 4.98 (4.60–5.19) | 5.92 (5.86–5.99)c | 5.13 (5.02–5.23)c,d | 6.03 (5.93–6.12)c,e |
| 2h OGTT (mmol/L)b | 5.53 (5.25–5.83) | 5.93 (5.71–6.16)c | 8.84 (8.54–9.11)c, d | 9.01 (8.75–9.27)c, d |
| SBP (mmHg)a | 134.00±15.89 | 137.04±17.91 | 142.76±15.39c | 140.72±18.38c |
| DBP (mmHg)a | 77.93±7.41 | 77.48±9.25 | 80.85±9.28 | 80.63±9.16 |
| WC (cm)b | 79.61 (77.75–81.51) | 82.79 (80.73–84.91)c | 83.22 (80.77–85.74)c | 83.33 (81.10–85.61)c |
| HC (cm)b | 91.65 (90.05–93.28) | 93.07 (91.77–94.39) | 92.53 (91.15–93.93) | 93.25 (91.62–94.92) |
| WHR b | 0.87 (0.86–0.88) | 0.89 (0.87–0.91)c | 0.90 (0.88–0.92)c | 0.89 (0.88–0.91)c |
| BMI (kg/m2)a | 23.52±3.39 | 24.19±3.88 | 24.41±2.99 | 24.57±3.18 |
| TC (mmol/L)b | 4.80 (4.60–5.01) | 4.92 (4.73–5.13) | 5.10 (4.83–5.39) | 4.74 (4.42–5.09) |
| TG (mmol/L)b | 1.22 (0.79–1.79) | 1.44 (1.26–1.64) | 1.58 (1.33–1.87) | 1.41 (1.22–1.62) |
| HDL-c (mmol/L)b | 1.23 (1.06–1.42) | 1.26 (1.20–1.32) | 1.22 (1.16–1.29) | 1.13 (1.06–1.21)c, d |
| LDL-c (mmol/L)b | 2.43 (2.04–3.00) | 2.42 (2.29–2.56) | 2.53 (2.34–2.72) | 2.50 (2.32–2.70) |
| Fasting insulin (mU/L)b | 5.54 (4.82–6.37) | 6.00 (5.32–6.77) | 6.95 (5.99–8.05)c | 6.44 (5.69–7.29) |
| HOMA-β indexb | 83.86 (72.35–97.21) | 49.74 (43.98–56.26)c | 87.19 (74.11–102.59) | 51.21 (45.16–58.07)c, e |
| HOMA-IR indexb | 1.14 (0.75–1.88) | 1.58 (1.40–1.78)c | 1.58 (1.36–1.84)c | 1.72 (1.52–1.96)c |
2h OGTT = 2 hour oral glucose tolerance test; BMI = body mass index; DBP=diastolic blood pressure; FPG=fasting plasma glucose; HC = hip circumference; HDL-c=high-density lipoprotein cholesterol; HOMA=homeostasis model assessment; I-IFG=isolated impaired fasting glucose; I-IGT=isolated impaired glucose tolerance; LDL-c=low-density lipoprotein cholesterol; Mixed IFG/IGT = mixed impaired fasting glucose and impaired glucose tolerance; NG = normal glucose; SBP = systolic blood pressure; TC=total cholesterol; TG=triglyceride; WC=waist circumference; WHR=waist-to-hip ratio.
Variable is described using mean and standard deviation and tested using ANOVA.
Variable is described using median and interquartile range, and tested using the Kruskal –Wallis H test.
P < 0.05 compared with the normal glucosec, IFGd, and IGT groupse.