Table 4.
Multivariate proportional hazard models predicting cardiovascular mortality by the teeth groups
| Exposure | Hazard ratio (95% confidence interval) |
P-value | |
|---|---|---|---|
| Model 1 | groups 1 (Nteeth‡=0) | 1.0 (reference) | – |
| groups 2 ((0 < Nteeth ≤ 10) | 0.90 (0.50–1.61) | 0.71 | |
| groups 3 (10< Nteeth ≤ 20) | 0.62 (0.28–1.39) | 0.24 | |
| groups 4 (Nteeth > 20) | 0.31 (0.10–0.70) | 0.005 | |
| ………… | ……… | …… | |
| as a trend across the groups | 0.70 (0.56–0.89) | 0.003** | |
|
| |||
| Model 2 | groups 1 | 1.0 (reference) | – |
| groups 2 | 1.05 (0.58–1.90) | 0.89 | |
| groups 3 | 0.62 (0.28–1.38) | 0.24 | |
| groups 4 | 0.37 (0.17–0.84) | 0.02 | |
| ………… | ……… | …… | |
| as a trend across the groups | 0.73 (0.57–0.94) | 0.02** | |
|
| |||
| Model 3 | groups 1 | 1.0 (reference) | – |
| groups 2 | 1.06 (0.62–1.93) | 0.85 | |
| groups 3 | 0.62 (0.27–1.41) | 0.24 | |
| groups 4 | 0.37 (0.17–0.85) | 0.02 | |
| ………… | ……… | …… | |
| as a trend across the groups | 0.73 (0.58–0.93) | 0.02** | |
|
| |||
|
Model 4 (Additional CRP>3mg/L adjusted) |
groups 1 | 1.0 (reference) | – |
| groups 2 | 1.12 (0.59–2.03) | 0.83 | |
| groups 3 | 0.65 (0.29–1.45) | 0.29 | |
| groups 4 | 0.40 (0.17–0.89) | 0.02 | |
| ………… | ……… | …… | |
| as a trend across the groups | 0.75 (0.57–0.97) | 0.03** | |
|
| |||
|
Model 5 (Additional CRP>5mg/L adjusted) |
groups 1 | 1.0 (reference) | – |
| groups 2 | 1.18 (0.65–2.15) | 0.58 | |
| groups 3 | 0.74 (0.33–1.65) | 0.46 | |
| groups 4 | 0.47 (0.21–1.07) | 0.07 | |
| ………… | ……… | …… | |
| as a trend across the groups | 0.80 (0.57–0.94) | 0.09** | |
|
| |||
|
Model 6 (Additional Fibrinogen > 3 g/L adjusted) |
groups 1 | 1.0 (reference) | – |
| groups 2 | 1.06 (0.59–1.92) | 0.83 | |
| groups 3 | 0.64 (0.29–1.44) | 0.28 | |
| groups 4 | 0.40 (0.18–0.90) | 0.03 | |
| ………… | ……… | …… | |
| as a trend across the groups | 0.75 (0.58–0.96) | 0.02** | |
‡
Nteeth= number of teeth
Model 1 adjusted for age, sex and smoking.
Model 2 adjusted for age, smoking (never, past and current smokers), hypertension, diabetes, and Total/HDL cholesterol ratio.
Model 3 adjusted for age, sex, smoking (never, past and current), hypertension, diabetes, Total/HDL cholesterol ratio, and education (in years).
Model 4 adjusted for all the covariates adjusted in model 2 and CRP>=3 mg/L.
Model 5 adjusted for all the covariates adjusted in model 2 and CRP >5 mg/L.
Model 6 adjusted for all the covariates adjusted in model 2 and fibrinogen > median (3.0 gm/L).
**
denotes significant at the α-level of 0.05.