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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Osteoarthritis Cartilage. 2013 Nov 2;22(1):51–62. doi: 10.1016/j.joca.2013.10.014

Table III.

MT mean values (95% CI, estimated differences) of each variable cross-sectionally (linear regression models adjusting for age, gender, BMI)

T1ρ Global (ms) Estimated difference 95% CI P-value T1ρ Articular layer (ms) Estimated difference 95% CI P-value T1ρ Bone layer (ms) Estimated difference 95% CI P-value
Baseline Control 34.57 5.5 2.5, 8.6 0.0005 41.02 4.5 1.056, 8 0.011 28.04 5.9 2.2, 9.6 0.0024
Lesion 40.66 47.28 33.75
1 Year Control 34.52 8 4.2, 11.9 0.0001 41.13 10.1 5.4, 14.9 <0.0001 27.68 5.8 1.579, 10 0.0079
Lesion 42.40 51.55 33.47
2 Year Control 35.38 6.6 2.7, 10.6 0.0017 42.30 6.3 1.864, 10.8 0.0069 28.33 5.1 0.4, 9.8 0.034
Lesion 41.46 49.23 32.21
3 Year Control 33.58 6.2 2.6, 9.7 0.0018 40.33 8.3 2.3, 14.4 0.0091 26.71 5.8 1.55, 10 0.0099
Lesion 38.11 47.38 30.12
T1ρ Contrast-horizontal Estimated difference 95% CI P-value T1ρ Contrast-vertical Estimated difference 95% CI P-value
Baseline Control 13.14 28 15, 41 <0.0001 106.24 118 63, 173 <0.0001
Lesion 42.96 260.12
1 Year Control 13.68 55 18.8, 91 0.0035 94.21 183 112, 253 <0.0001
Lesion 64.90 307.70
2 Year Control 8.59 50 19.4, 81 0.0023 106.12 110 33, 187 0.0064
Lesion 57.93 256.48
3 Year Control 13.83 –2.187 –10.35, 6 0.58 98.72 –7.996 –40.63, 25 0.62
Lesion 10.87 97.71
T1ρ Entropy-horizontal Estimated difference 95% CI P-value T1ρ Entropy-vertical Estimated difference 95% CI P-value
Baseline Control 5.09 –0.045 –0.279, 0.188 0.7 5.21 –0.07 –0.28, 0.14 0.51
Lesion 5.08 5.14
1 Year Control 5.02 0.248 0.101, 0.395 0.0014 5.23 0.058 –0.125, 0.24 0.53
Lesion 5.27 5.26
2 Year Control 4.97 0.355 0.188, 0.522 0.0001 5.22 0.187 –0.006, 0.38 0.05
Lesion 5.34 5.37
3 Year Control 5.11 0.267 0.024, 0.51 0.033 5.27 0.524 0.207, 0.841 0.0024
Lesion 5.39 5.82
T1ρ Variance-horizontal Estimated difference 95% CI P-value T1ρ Variance-vertical Estimated difference 95% CI P-value
Baseline Control 97.44 124 70, 179 <0.0001 84.71 89 44, 134 0.0002
Lesion 262.71 212.65
1 Year Control 95.14 201 138, 264 <0.0001 87.72 159 104, 215 <0.0001
Lesion 315.53 257.53
2 Year Control 100.03 133 79, 187 <0.0001 86.38 120 71, 169 <0.0001
Lesion 258.85 226.33
3 Year Control 103.72 30 –3.777, 64 0.079 95.90 24 –13.87, 62 0.2
Lesion 139.75 122.61
T2 Global mean (ms) Estimated difference 95% CI P-value T2 Articular layer (ms) Estimated difference 95% CI P-value T2 Bone layer (ms) Estimated difference 95% CI P-value
Baseline Control 28.09 3.7 1.216, 6.3 0.0042 31.15 4.1 1.301, 6.9 0.0045 24.97 3.6 0.017, 7.2 0.049
Lesion 33.97 37.40 30.76
1 Year Control 25.96 6.6 4, 9.2 <0.0001 29.30 7.9 5.4, 10.4 <0.0001 22.56 5.5 1.765, 9.3 0.0047
Lesion 32.60 37.77 27.74
2 Year Control 24.89 7.9 4.8, 11 <0.0001 28.52 9.3 5.9, 12.6 <0.0001 21.17 6.8 3.2, 10.5 0.0006
Lesion 33.22 38.86 27.88
3 Year Control 26.50 7.3 3.8, 10.8 0.0003 29.56 6.9 2.2, 11.6 0.0056 23.28 8 3.7, 12.3 0.0009
Lesion 32.80 36.53 29.30
T2 Contrast-horizontal Estimated difference 95% CI P-value T2 Contrast-vertical Estimated difference 95% CI P-value
Baseline Control 15.86 23 6.6, 40 0.0066 115.95 123 52, 194 0.001
Lesion 41.70 262.36
1 Year Control 11.06 14.2 8, 20 <0.0001 80.42 173 106, 240 <0.0001
Lesion 25.00 285.26
2 Year Control 6.96 11.6 2.1, 21 0.019 73.21 127 68, 186 0.0001
Lesion 23.57 241.23
3 Year Control 7.05 12.7 3.8, 22 0.0073 108.58 68 –33.1, 169 0.18
Lesion 21.21 172.17
T2 Entropy-horizontal Estimated difference 95% CI P-value T2 Entropy-vertical Estimated difference 95% CI P-value
Baseline Control 4.94 0.146 –0.033, 0.326 0.11 5.18 –0.005 –0.23, 0.22 0.97
Lesion 5.14 5.14
1 Year Control 4.88 0.313 0.135, 0.491 0.0009 5.15 0.154 –0.05, 0.35 0.13
Lesion 5.18 5.31
2 Year Control 4.77 0.372 0.162, 0.582 0.0011 5.19 0.242 –0.02, 0.51 0.071
Lesion 5.15 5.38
3 Year Control 4.82 0.25 0.051, 0.45 0.017 5.17 0.226 –0.02, 0.47 0.068
Lesion 5.12 5.46
T2 Variance-horizontal Estimated difference 95% CI P-value T2 Variance-vertical Estimated difference 95% CI P-value
Baseline Control 108.51 137 77, 197 <0.0001 96.96 106 54, 158 0.0001
Lesion 287.60 198 238.24
1 Year Control 82.89 143, 254 <0.0001 73.23 152 108, 196 <0.0001
Lesion 304.81 240.65
2 Year Control 75.31 118 66, 171 <0.0001 64.60 96 54, 139 <0.0001
Lesion 229.27 190.26
3 Year Control 89.83 110 43, 177 0.0026 77.43 92 37, 147 0.0022
Lesion 205.07 172.35

The bold indicates significance at P < 0.05.