Table 1.

Average mean absolute relative difference (MARD) values at three weeks for DTR chimeric mouse studies.

Cumulative 3 weeks mean MARD data Mann–Whitney U tests	C57BL/6 average mean MARD = 24.76 ± 11.27% n = 20	C57BL/6 DT Inj average mean MARD = 22.71 ± 7.88% n = 7	Ch No DT injection average mean MARD = 25.22 ± 8.70% n = 12	Ch DT injected average mean MARD = 12.46 ± 2.97% n = 6
C57BL/6 average mean MARD = 24.76 ± 11.27% n = 20	–	1.0000	0.8032	0.0003
C57BL/6 DT Inj average mean MARD = 22.71 ± 7.88% n = 7		–	0.5391	0.0140
Ch No DT Injection average mean MARD = 25.22 ± 8.70%  n = 12			–	0.0004
Ch DT Injected average mean MARD = 12.46 ± 2.97% n = 6				–

Table 1. Presents the Average Mean Absolute Relative Difference (MARD) values at three weeks for DTR Chimeric Mouse Studies. Error values following the ± are standard deviations from the average of the individual treatment group’s MARD values. p-values within the boxes represent the statistical significance of the comparisons of the two treatment groups indicated in the axes, calculated by Mann–Whitney U tests, as non-parametric equivalents to student t-tests, where appropriate. Mann–Whitney U tests were conducted because only the Chimeric No DT injected and C57BL/6 DT injected treatment groups had normally distributed mean MARD values.