Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potential sites of pathogenic variants resulting in quantitative von Willebrand factor (VWF) traits (type 1 and 3 von Willebrand disease). Genetic variables anywhere along the VWF life cycle from the regulation of gene expression to protein clearance may result in quantitative phenotypes. In some instances, single variables may produce a dominant effect but in mild/moderate quantitative phenotypes combinations of variables may be more prevalent.
