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. Author manuscript; available in PMC: 2014 Feb 25.
Published in final edited form as: Am J Addict. 2013 Apr 11;22(6):590–597. doi: 10.1111/j.1521-0391.2013.12014.x

Table 2.

Symptom counts and mean severity ratings of side effects from nicotine patch, active nasal spray, and placebo nasal spray.

Patch + Active Condition Patch + Placebo Condition
Count Severity Count Severity
Patch
 Skin irritation 1 2 - -
 Heart Rate > 100 1 - 1 -
 Dizziness - - - -
 Nausea - - - -
 Abdominal Discomfort 1 1 - -
Nasal Spray
 Nasal irritation 17 2.2 11 1.8
 Throat irritation 13 2.0 1 3.0
 Eyes watering 17 1.9 10 1.7
 Heart rate > 100 1 - 1 -
 Dizziness/Light-headed 4 1.5 3 1.3
 Nausea - - - -
 Hands or feet cold 1 3.0 2 2.0

Notes. Severity of side effects were rated on a four point scale (1 = minimal, 2 = mild, 3 = moderate, 4 = severe); Across reported side effects, severity ratings did not differ across active and placebo spray conditions.