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. Author manuscript; available in PMC: 2014 Feb 25.
Published in final edited form as: J Nurs Scholarsh. 2011 Jul 29;43(3):274–281. doi: 10.1111/j.1547-5069.2011.01406.x

Table 2.

Steps to Enhance the Biobehavioral Inquiry of Fatigue

1. Refine the homogeneity of the fatigue conceptualization
2. Operationalize the refined conceptualization of fatigue.
3. Develop valid and reliable measures of fatigue.
4. Examine theoretically related genotypes (e.g., through candidate gene studies).
5. Explore the contribution of the genome (e.g., through GWAS).
6. Examine the epigenetic triggers of fatigue.

GWAS = genomewide association study.