Table 2.
Computed tomographic colonography accuracy for colonic surveillance after colorectal cancer resection
Patients |
Sensitivity |
Specificity | ||||
n | Characteristics | Target lesions1 | Per-patient | Per-lesion | ||
Amitai et al[64] | 29 | Routine surveillance | (Peri) anastomotic recurrence | 100% (2/2) | 100% (2/2) | NA |
Metachronous polyps | 100% (NA) | 93% (28/30) | 71% (NA) | |||
Fletcher et al[65] | 50 | Routine surveillance | (Peri) anastomotic recurrence | 100% (2/2) | NA | 94% (45/48) |
Metachronous polyps ≥ 5 mm | 60% (3/5) | NA | 84% (38/45) | |||
You et al[67] | 80 | Suspicion of recurrence | (Peri) anastomotic recurrence | 100% (51/51) | 100% (51/51) | 83% (24/29) |
Kim et al[68] | 548 | Routine surveillance | Metachronous cancer and (peri) anastomotic recurrence | 100% (6/6) | 100% (7/7) | 93.1% (421/452) |
Advanced neoplasia2 | 81.8% (18/22) | 80.8% (21/26) | ||||
All adenomatous lesions3 ≥ 6 mm | 80% (52/65) | 78.5% (62/79) |
Data are percentages with the actual numbers of patients and lesions are presented in parentheses.
Histology and size are not specified unless provided in the original studies;
Advanced neoplasia includes both advanced adenomas (≥ 10 mm in size or with a substantial villous component or high-grade dysplasia) and adenocarcinomas;
Both adenomas and adenocarcinomas are included. NA: Not available.