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Effect of pretreatment with the 5-HT2A antagonist M100907 on the locomotor response to 25 mg/kg mescaline. Mice were pretreated with 0.03 mg/kg M100907 (A) or 0.1 mg/kg M100907 (B). Mice used were male C57BL/6J. Data are presented as group means±SEM for successive 10-min intervals. *p<0.05, **p<0.01, significant difference from vehicle control group. #p<0.05, ##p<0.001, significant difference from mescaline alone.
