Table 4.
Cellular composition of brain regions
| Neocortex: | |||||||
|---|---|---|---|---|---|---|---|
| Age | % Neurons | # cells (in millions) |
# neurons (in millions) |
# non-neurons (in millions) |
# cells/gram (in millions) |
# neurons/gram (in millions) |
# non-neurons/gram (in millions) |
|
| |||||||
| P18 | 60.55 ± 9.44 | 1.637 ± .058 | .985 ± .139 | .653 ± .163 | 180.032 ± 13.690 | 109.054 ± 18.773 | 70.977 ± 18.490 |
| P35 | 44.44 ± 9.21 | 1.580 ±.141 | .743 ± .093 | .836 ± .093 | 47.043 ± 6.952 | 22.792 ± 5.787 | 24.250 ± 3.103 |
| P56 | 43.52 ± 11.69 | 2.027 ± .220 | .970 ± .131 | 1.057 ± .131 | 40.454 ± 3.142 | 19.059 ± 6.024 | 21.394 ± 2.928 |
| P180 | 22.04 ± 3.63 | 3.224 ± .440 | .748 ± .283 | 2.476 ± .283 | 44.578 ± 4.136 | 10.111± 2.132 | 34.468 ± 2.678 |
| P270-365 | 33.55 ± 3.71 | 2.606 ± .308 | .847 ± .050 | 1.760 ± .306 | 37.901 ± 3.146 | 12.509 ± 1.226 | 25.391 ± 3.297 |
| >P365 | 25.62 ± 4.86 | 3.030 ± .209 | .803 ± .199 | 2.227 ± .120 | 42.067 ± 2.623 | 10.917 ± 2.545 | 30.779 ± 1.675 |
| Subcortical Regions: | |||||||
| Age | % Neurons |
# cells
(in millions) |
# neurons
(in millions) |
# non-neurons
(in millions) |
# cells/gram
(in millions) |
# neurons/gram
(in millions) |
# non-neurons/gram
(in millions) |
|
| |||||||
| P18 | 77.40 ± 5.00 | 3.184 ± .185 | 2.486 ± .267 | .698 ± .117 | 60.693 ± 3.293 | 47.436 ± 5.288 | 13.257 ± 2.198 |
| P35 | 6.77 ± 2.67 | 7.187 ± .659 | .503 ± .199 | 6.684 ± .610 | 51.355 ± 4.339 | 3.789 ± 1.677 | 47.565 ± 3.351 |
| P56 | 6.17 ± .69 | 8.240 ± .287 | .512 ± .066 | 7.728 ± .252 | 52.090 ± 1.759 | 3.186 ± .286 | 48.904 ± 1.868 |
| P180 | 6.30 ± .99 | 12.496 ± 1.009 | .803 ± .151 | 11.693 ± .912 | 44.941 ± 1.637 | 2.868 ± .498 | 42.073 ± 1.344 |
| P270-365 | 4.55 ± .32 | 12.073 ± 1.043 | .556 ± .079 | 11.517 ± .971 | 44.636 ± 3.108 | 2.053 ± .277 | 42.582 ± 2.853 |
| >P365 | 7.25 ± .90 | 13.147 ± 6.223 | .959 ± .172 | 12.044 ± .632 | 42.577 ± 2.326 | 3.079 ± .510 | 38.885 ± 2.541 |
| Cerebellum: | |||||||
| Age | % Neurons |
# cells
(in millions) |
# neurons
(in millions) |
# non-neurons
(in millions) |
# cells/gram
(in millions) |
# neurons/gram
(in millions) |
# non-neurons/gram
(in millions) |
|
| |||||||
| P18 | 86.93 ± 4.55 | 1.489 ± .191 | 1.282 ± .135 | .207 ± .086 | 229.061 ± 34.503 | 197.596 ± 26.204 | 31.465 ± 13.562 |
| P35 | 19.31 ± 8.14 | 11.084 ± .535 | 2.020 ± .740 | 9.064 ± 1.151 | 307.204 ± 26.825 | 65.787 ± 34.782 | 241.417 ± 19.457 |
| P56 | 30.82 ± 5.67 | 19.223 ± .522 | 5.954 ± 1.118 | 13.269 ± 1.039 | 303.494 ± 9.089 | 94.534 ± 18.142 | 208.961 ± 14.605 |
| P180 | 12.75 ± 4.20 | 30.496 ± 2.883 | 4.048 ± 1.353 | 26.448 ± 2.328 | 259.794 ± 15.348 | 34.082 ± 11.099 | 255.712 ± 14.011 |
| P270-365 | 9.97 ± 6.32 | 27.766 ± 2.378 | 2.537 ± 1.446 | 25.229 ± 3.305 | 241.285 ± 11.614 | 23.322 ± 14.085 | 217.963 ± 20.750 |
| >P365 | 8.45 ± 4.5 | 24.796 ± 1.969 | 2.018 ± .961 | 22.778 ± 2.308 | 200.907 ± 12.770 | 17.064 ± 8.764 | 183.843 ± 14.757 |