Fig. 2.
Trabecular bone mass is dramatically decreased in Kal-KO mice. (A) Three-dimensional reconstruction of micro-CT images of distal femurs of 14 week old female mice. (B) Trabecular bone parameters of 14 week female (WT and Kal-KO) mice and male (WT and Kal-KO) mice (n = 6, 7, 11 and 9 mice, respectively). Bone volume/total volume (BV/TV), thickness (TbTh) and trabecular number (TbN) were determined. Results shown are mean ± SEM relative to sex-matched controls. Statistically significance (p < 0.05) compared to sex-matched WT mice is indicated by an asterisk.