Table 3.

Linear regression results for possible confounders

Independent variable Confounder	N	F-value	P-value	Unstandardized effect (B)	SD	t-value	P-value
Treatment dose	91	7.363	>0.001*
Age during first treatment				8.6 mC/year	2.7	3.189	0.002**
Female sex				101.8 mC	85	1.198	0.234
Cardiovascular disease				−112.2 mC	96.2	−1.166	0.247
Motor seizure duration	76	3.376	0.009*
Age during first treatment				−0.2 sec/year	0.1	−2.357	0.021**
Female sex				−1.157 sec	3.3	−0.351	0.726
Cardiovascular disease				0.681 sec	3.1	0.217	0.829
Seizure duration on EEG	81	2.619	0.031*
Age during first treatment				−0.2 sec/year	0.2	−1.315	0.192
Female sex				−8.2 sec	4.7	−1.756	0.083
Cardiovascular disease				3.377 sec	5.4	0.626	0.533
Change in diastolic blood pressure†	80	3.147	0.012*
Age during first treatment				−0.2 mmHg/year	0.1	−2.003	0.049
Female sex				5.6 mmHg	3.2	1.75	0.084
Cardiovascular disease				−2.5 mmHg	3.6	−0.691	0.492
Change in heart rate†	74	2.653	0.03*
Age during first treatment				−0.2 bpm‡	0.2	−1.346	0.183
Female sex				6.3 bpm	4.8	1.333	0.187
Cardiovascular disease				6.1 bpm	5.5	1.097	0.276

Notes:

^*Statistically significant difference in one-way analysis of variance;

^**statistically significant difference for a two-tailed t-test (P<0.05);

^†change was calculated by subtracting the value before treatment from the value after treatment.

Abbreviations: bpm, beats per minute; EEG, electroencephalography; SD, standard deviation; sec, seconds.