Table 1.

Subunit-specific modulation of ASICs by stomatin family proteins. Different stomatin family members modulate specific ASIC subunits in different ways. ‘?’ represents combinations that have not yet been examined; STOML2 and podocin have not yet been assessed and thus are absent from the table

	Stomatin	STOML1	STOML3
ASICIa	No effect	Inhibits current amplitude	No effect
ASICIb	?	No effect	?
ASIC2a	Increases inactivation speed	No effect	Inhibits current amplitude
ASIC2b	Homomers not activated by H+
ASIC3	Inhibits current amplitude	Increases inactivation speed	Inhibits current amplitude
ASIC4	Homomers not activated by H+