TABLE 2.
Acclimation Temperature | Genotype | n | Resting Metabolic Ratea | Maximal Metabolic Rate after NAa | NST Capacity after NAa |
30°C | WT | 5 | 36.65 ± 1.6 | 75.97 ± 8.9 | 39.32 ± 7.5 |
UCP1-KO | 7 | 41.17 ± 1.3 | 61.07 ± 4.7 | 19.90 ± 4.2* | |
18°C | WT | 12 | 46.23 ± 0.9 | 175.21 ± 3.6 | 128.98 ± 3.8 |
UCP1-KO | 16 | 46.01 ± 0.9 | 96.48 ± 2.9* | 50.47 ± 2.8* | |
5°C | WT | 5 | 47.21 ± 2.1 | 200.77 ± 9.4 | 153.56 ± 10.1 |
UCP1-KO | 7 | 47.52 ± 2.5 | 107.46 ± 8.3* | 59.94 ± 7.0* |
NST capacity is the difference between resting metabolic rate and maximum metabolic rate after NA injection. UCP1-KO and WT mice were sequentially acclimated to ambient temperatures of 30°C, 18°C, and 5°C. Values are means ± SEM. Statistically significant differences between the genotypes at each acclimation temperature (P ≤ 0.05) are indicated with *.
Values are in milliliters of O2 per hour.