TABLE 1.
Plasma parameters in adipose ABCA1 knockout mice
| ABCA1+/+ | ABCA1−ad/−ad | P | |
| Chow | |||
| Cholesterol | 2.51 ± 0.09 | 2.21 ± 0.09 | 0.034 |
| HDL | 2.10 ± 0.07 | 1.96 ± 0.08 | 0.234 |
| TG | 1.06 ± 0.06 | 1.22 ± 0.04 | 0.030 |
| NEFA | 0.31 ± 0.017 | 0.31 ± 0.014 | 0.780 |
| Glucose | 9.01 ± 0.28 | 9.91 ± 0.22 | 0.017 |
| Insulin | 0.84 ± 0.09 | 0.96 ± 1.00 | 0.410 |
| HFHC | |||
| Cholesterol | 3.94 ± 0.22 | 3.59 ± 0.10 | 0.260 |
| HDL | 3.25 ± 0.23 | 3.07 ± 0.31 | 0.643 |
| TG | 0.71 ± 0.01 | 0.79 ± 0.08 | 0.047 |
| NEFA | 0.36 ± 0.043 | 0.43 ± 0.041 | 0.340 |
| Glucose | 8.65 ± 0.49 | 9.45 ± 0.21 | 0.240 |
| Insulin | 1.11 ± 0.09 | 1.92 ± 0.32 | 0.028 |
Blood was drawn from the saphenous vein after 4 h fasting and assessed for the parameters above. Values are means ± SEM. P values reaching statistical significance are bold. Chow: n = 15 (cholesterol, TG, glucose, HDL), n = 5–10 (insulin, NEFA); HFHC: n = 8–6.