TABLE 4.

Hepatic lipids in mice of the indicated genotype on LD

	TG	TC	FC	CE	PL	FFA
Mttpf/f (n = 11)	84.3 ± 5.8a	122.7 ± 15.4a	23.9 ± 1.9a	98.7 ± 13.4a	74.3 ± 3.3a	42.6 ± 4.8a
Mttp-LKO (n = 8)	101.9 ± 12.1a	71.1 ± 5.5b	19.6 ± 1.8a	51.6 ± 5.3b	56.1 ± 2.4b	37.9 ± 3.1a
L-Fabp−/− (n = 5)	119.9 ± 14.4a	98.4 ± 6.7ab	38.7 ± 2.5b	59.8 ± 6.4ab	76.5 ± 8.3a	41.4 ± 2.8a
DKO (n = 17)	98.8 ± 4.8a	74.7 ± 3.7b	20.9 ± 0.7a	53.7 ± 3.6b	62.6 ± 2.2b	39.3 ± 4.6a

Mice from four experimental groups were fed a LD (C, D) for 2 weeks. Hepatic lipids were extracted and analyzed (see Materials and Methods). Hepatic lipid content is expressed as mean ± SE (μg/mg protein), except FFA (nmol/mg protein). The difference between values associated with different superscript letters for the parameters indicated in each vertical column is statistically significant (P < 0.05). TG, triglyceride; TC, cholesterol; FC, free cholesterol; CE, cholesterol ester; PL, phospholipids.