. 2014 Mar;55(3):540–548. doi: 10.1194/jlr.M046342

TABLE 7.

Serum lipids and ALT level in ASO-treated mice of the indicated genotype

	TG (mg/dl)	TC (mg/dl)	ALT (IU/l)
WT-C-ASO	15.5 ± 4.9	134.8 ± 7.2^a	142.9 ± 14.2^a
WT-M-ASO	12.8 ± 2.7	93.4 ± 10.5^b	182.0 ± 18.0^a
L-Fabp^−/−-C-ASO	9.7 ± 1.9	183.7 ± 12.7^c	158.9 ± 20.5^a
L-Fabp^−/−-M-ASO	14.5 ± 5.7	90.0 ± 7.7^b	163.09 ± 7.8^a

WT and L-Fabp^−/− mice received either control-ASO or Mttp-ASO for four weeks and were fed a LD for the final 2 weeks, while continuing ASO injection (n = 4–5 per group). Sera were collected after overnight fasting and serum lipids and ALT assayed. The difference between values associated with different superscript letters for the parameters indicated in each vertical column is statistically significant (P < 0.05). TG, triglyceride; TC, cholesterol.