Table 3.
Summary of single channel properties
| 2A/2A | L812M/2A | L812M/L812M | |
|---|---|---|---|
| Open probability | 0.23 ± 0.04 | 0.58 ± 0.03 # | 0.64 ± 0.03 # |
| Mean open time, ms | 2.6 ± 0.17 | 5.1 ± 0.33 # | 5.2 ± 0.34 # |
| τ1, ms (%) | 0.11 ± 0.02 (19%) | 0.18 ± 0.07# (8%#) | 0.31 ± 0.11# (8%#) |
| τ2, ms (%) | 3.2 ± 0.16 (81%) | 5.6 ± 0.34# (92%#) | 5.6 ± 0.34# (92%#) |
| Mean shut time, ms | 13 ± 4.2 | 3.6 ± 1.2 # | 2.0 ± 0.04 # |
| τ1, ms (%) | 0.27 ± 0.01 (32%) | 0.06 & (40%) | 0.06 & (41%) |
| τ2, ms (%) | 1.0 ± 0.11 (34%) | 0.52 ± 0.07# (34%) | 0.43 ± 0.08# (26%) |
| τ3, ms (%) | 3.5 ± 0.38 (31%) | 1.5 ± 0.16# (20%) | 1.2 ± 0.27# (29%) |
| τ4, ms (%)ξ | 29 ± 7.9 (1.8%) | 25 ± 21 (5.7%) | 41 ± 31 (3.8%) |
| τ5, ms (%)ξ | 940 ± 193 (1.2%) | 823 ± 210 (0.3%) | 906 ± 66 (0.2%) |
| Major amplitude (pA) | 6.7 ± 0.1 | 6.9 ± 0.1 | 6.9 ± 0.1 |
| γ, pS | 84 ± 1.6 | 85 ± 1.7 | 85 ± 1.2 |
| n | 4 | 4 | 4 |
The data were expressed as Mean ± SEM.
#
p < 0.05 compared to 2A/2A; one way ANOVA, Tukey post hoc
&
The briefest shut time component was not well described due to the imposed resolution
ξ
Statistical tests were not run on the two slowest shut time components given the limited number of events underlying these components