Table 4.
Regression coefficients of individual models predicting global, affective, and somatic depressive symptoms from continuous allostatic load components, overall allostatic load summary score, and other covariates in final sample (sample size varies).
| Global Depressive Symptoms | Model N/R2 | Log (Affective Symptom Sub-scale Score) | Model N/R2 | Somatic Symptom Sub-Scale Factor Score | Model N/R2 | ||
|---|---|---|---|---|---|---|---|
| Coefficient (95% CI)a | Coefficient (95% CI)a | Coefficient (95% CI)a | |||||
| Initial Modelb | Allostatic Load | 1.47 (0.64, 2.30) | 124/11.3 | 0.18 (0.078, 0.28) | 125/9.6 | 0.68 (0.33, 1.04) | 123/12.4 |
| Diurnal cortisol slope | 72.98 (14.77, 131.20) | 122/6.5 | 4.46 (−0.038, 8.95) | 125/3.4 | 31.72 (5.61, 57.82) | 122/6.5 | |
| IL-6 IGF-1 |
−0.12 (−0.78, 0.55) | 123/2.0 | −0.0053 (−0.088, 0.078) | 125/0.4 | 0.048 (−0.25, 0.35) | 123/2.1 | |
| Resting Heart Rate | −0.019 (−0.06, 0.02) | 124/3.1 | −0.0027 (−0.0072, 0.0017) | 125/1.6 | −0.0071 (−0.023, 0.009) | 123/2.7 | |
| Waist-to-hip Ratio | 0.11 (−0.02, 0.24) | 123/4.1 | 0.017 (0.00084, 0.033) | 125/3.8 | 0.046 (−0.012, 0.10) | 123/4.0 | |
| Systolic BP Diastolic BP |
16.62 (0.29, 31.18) | 122/5.1 | 1.74 (−0.34, 3.82) | 125/2.6 | 9.67 (2.36, 16.97) | 123/7.3 | |
| 0.030 (−0.065, 0.12) | 123/2.2 | 0.0093 (−0.0023, 0.021) | 125/2.4 | 0.0094 (−0.032, 0.051) | 123/2.2 | ||
| 0.067 (−0.11, 0.25) | 123/2.3 | 0.013 (−0.009, 0.035) | 125/1.5 | 0.012 (−0.069, 0.092) | 123/2.1 | ||
|
| |||||||
| Final Modelc | Allostatic Load | 1.21 (0.38, 2.05) | 124/20.2 | 0.14 (0.040, 0.24) | 125/19.9 | 0.60 (0.23, 0.97) | 123/17.7 |
| Diurnal cortisol slope | 72.05 (14.71, 129.40) | 122/16.6 | 4.12 (−0.22, 8.46) | 125/17.2 | 30.84 (4.76, 56.91) | 122/14.3 | |
| IL-6 IGF-1 |
−0.10 (−0.76, 0.55) | 123/12.3 | −0.0043 (−0.084, 0.076) | 125/14.7 | 0.067 (−0.23, 0.36) | 123/10.5 | |
| Resting Heart Rate | −0.0077 (−0.044, 0.028) | 124/14.6 | −0.0013 (−0.0056, 0.0030) | 125/15 | −0.0036 (−0.019, 0.012) | 123/10.5 | |
| Waist-to-hip Ratio | 0.093 (−0.040, 0.22) | 123/13.8 | 0.014 (−0.0016, 0.030) | 125/16.9 | 0.036 (−0.022, 0.094) | 123/11.5 | |
| Systolic BP Diastolic BP |
15.46 (−1.18, 32.10) | 122/14.9 | 1.33 (−0.71, 3.37) | 125/15.9 | 8.39 (0.97, 15.81) | 123/14.1 | |
| 0.025 (−0.069, 0.12) | 123/12.4 | 0.0088 (−0.0024, 0.020) | 125/16.4 | 0.0059 (−0.036, 0.048) | 123/10.4 | ||
| 0.10 (−0.080, 0.28) | 123/13.2 | 0.016 (−0.0053, 0.038) | 125/16.3 | 0.026 (−0.056, 0.11) | 123/10.7 | ||
a
Bold coefficients signify two-sided significance at 0.05 level
b
Initial model covariates include: age and sex
c
Final model covariates include: age, sex, educational attainment, estimated annual income, physical activity, and antidepressant medication usage