Table 2.
Vascular measurements | Linear Mixed Model: changes due to the 1-year interventions | ||||||
---|---|---|---|---|---|---|---|
Exercise training | No exercise training | Time*Training | Time*Medication | Time*Training Medication | |||
Alagebrium | placebo | Alagebrium | placebo | p-value | p-value | p-value | |
Common femoral artery diameter (mm) | 0.043 | 0.948 | 0.837 | ||||
Baseline | 9.5±0.9 | 10.1±1.3 | 10.7±1.8 | 9.8±1.6 | |||
6 months | 10.0±1.0 | 10.5±1.4 | 10.9±1.5 | 9.9±1.6 | |||
12 months | 10.1±1.0 | 10.6±1.3 | 10.9±1.5 | 10.0±1.6 | |||
Arterial stiffness, pulse wave velocity (m/s) | 0.425 | 0.106 | 0.886 | ||||
Baseline | 13.3±5.4 | 11.0±3.2 | 13.2±4.3 | 11.5±3.0 | |||
6 months | 11.7±3.7 | 10.8±2.4 | 12.7 ±2.8 | 12.4±3.4 | |||
12 months | 12.3±4.1 | 11.4±2.6 | 12.2±1.7 | 12.7±3.9 |
Data are presented as mean ± standard deviation.