Table 2. The 20 genes most strongly upregulated by PaCDase in 3D cultured keratinocytes.
| Name | ratio | RefSeq_ID | description |
| NP_853640.1 | 11.1 | NM_181609 | Keratin-associated protein 19-3 |
| KRTAP3-2 | 11.1 | NM_031959 | Keratin-associated protein 3-2 |
| DMBX1 | 8.4 | NM_172225 | diencephalon/meSensephalon homeobox 1 isoform |
| KRTAP19-1 | 8.4 | NM_181607 | Keratin-associated protein 19-1 |
| EDN1 | 7.8 | - | Endothelin-1 |
| TNF-α | 7.6 | NM_000594 | Tumor necrosis factor |
| NP_853642.1 | 7.4 | NM_181611 | Keratin-associated protein 19-5 |
| IL8 | 7.0 | NM_000584 | Interleukin-8 |
| NP_004684.1 | 6.0 | NM_004693 | cytokeratin type II |
| SPOCD1 | 5.8 | - | SPOC domain containing 1 |
| FOS | 5.7 | NM_005252 | Proto-oncogene protein c-fos (Cellular oncogene fos) |
| KCTD12 | 5.6 | NM_138444 | Potassium channel tetramerization domain containing protein 12 (Pfetin) |
| RHOI_HUMAN | 5.6 | NM_004675 | Rho-related GTP-binding protein RhoI. |
| CLDN4 | 5.5 | NM_001305 | Claudin-4 (Clostridium perfringens enterotoxin receptor) |
| CXCL1 | 5.2 | - | Growth regulated protein alpha precursor (CXCL1) |
| JUN | 4.9 | NM_002228 | Transcription factor AP-1 (Activator protein 1) |
| GADD45G | 4.9 | NM_006705 | Growth arrest and DNA-damage-inducible protein GADD45 gamma |
| ADAMTS1 | 4.9 | NM_006988 | ADAMTS-1 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 1) |
| TNFAIP6 | 4.6 | NM_007115 | Tumor necrosis factor-inducible protein TSG-6 precursor |
| CTGF | 4.5 | NM_001901 | Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24). |
The results shown are representative data of 3 experiments.