Skip to main content
. 2014 Feb 25;9(2):e89412. doi: 10.1371/journal.pone.0089412

Table 4. Relevant histopathological findings.

Observations Tissue Groups:
3%INF 14%INF 3%NI 14%NI
Multifocal to coalescing granulomatous infiltrates Liver + (7/12) + (3/12) 0 (12/12) 0 (12/12)
++ (3/12) ++ (7/12)
+++ (2/12) +++ (2/12)
Spleen + (2/12) + (2/12) 0 (12/12) 0 (12/12)
++ (9/12) ++ (7/12)
+++ (1/12) +++ (3/12)
Giant multinucleated cells with intra-cytoplasmic concentric lamellar mineral Liver 0 (3/12) 0 (4/12) 0 (12/12) 0 (12/12)
+ (9/12) + (8/12)

Severity of the histopathological findings: non-existant (0), mild (+), moderate (++), severe (+++).

(n/n) – Number of animals with the given severity of the histopathological feature within each group.